| Customization: | Available |
|---|---|
| Type: | Health Care |
| Function: | Anti-Aging, Anti-Wrinkle |
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Product Name: superoxide dismutase
Cas No.: 9054-89-1
EINECS: 232-943-0
Appearance: White Powder
Enzyme Activity: 1000U/mg-50000U/mg
PH: 6.5~7.6
Protein content: 85%
Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide(H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2−).
SOD enzymes deal with the superoxide radical by alternately adding or removing an electron from the superoxide molecules it encounters, thus changing the O2− into one of two less damaging species: either molecular oxygen (O2) or hydrogen peroxide (H2O2). This SOD-catalyzed dismutation of superoxide may be written, for Cu,Zn SOD, with the following half-reactions:
Cu2+-SOD + O2− → Cu+-SOD + O2
Cu+-SOD + O2− + 2H+ → Cu2+-SOD + H2O2
The general form, applicable to all the different metal-coordinated forms of SOD, can be written as follows:
M(n+1)+-SOD + O2− → Mn+-SOD + O2
Mn+-SOD + O2− + 2H+ → M(n+1)+-SOD + H2O2.
where M = Cu (n=1) ; Mn (n=2) ; Fe (n=2) ; Ni (n=2).
In a series of such reactions, the oxidation state and the charge of the metal cation oscillates between n and n+1: +1 and +2 for Cu, or +2 and +3 for the other metals.
1. There is a significant effect of sunscreen, light skin darkening is mainly due to oxygen free radical damage, Superoxide Dismutase can effectively prevent skin by ionizing radiation (especially UV) damage, which play a sunscreen effect;
2. Superoxide Dismutase for the antioxidant enzyme, can effectively prevent skin aging, freckle, wrinkle;
3. there are significant anti-inflammatory effects, prevention and treatment of skin diseases have a certain effect;
4. Superoxide Dismutase has a preventive role in scar formation.
1. SOD (superoxide dismutase) enzyme as a medicinal raw material application is the future mainstream medicine care.
SOD is able to cause certain diseases superoxide anion (O2·) Clear to eliminate its cause, and therefore where due (O 2 - ·) disease caused by too much, you can use the SOD control. SOD in foreign countries not officially on the Pharmacopoeia, but there are products sold in the United States, Germany and Australia and other countries.
SOD is a specific superoxide anion radical scavenger, so it can be used in the treatment of autoimmune diseases (such as rheumatoid arthritis, emphysema, lupus, etc.), trade names Orgotein, Ormetein, Ontosein paiosein and Paroxinom and so on.
In our country has been approved by the Ministry of Health clinical drug approval committee. According to reports, SOD for the treatment of oxygen toxicity, acute inflammation and edema, autoimmune disease, emphysema, radiation disease, intestinal ischemia or reperfusion syndrome and senile cataract, etc., can also be used as anti-aging drug.
2. SOD (superoxide dismutase) in the food industry .
As a food additive or food supplements can be added to enhance the SOD in anti-aging, anti-inflammatory, anti-radiation, anti-fatigue and other health effect. SOD can also be used as an antioxidant in the canned food, juice, beer and other foods, to prevent overeating enzymes are caused by oxidative product deterioration and corruption, but also as a preservative of fruits and vegetables. When orally effective SOD was confirmed after the world competing SOD developed as a food additive used in two ways:
(1) as an antioxidant, and, like other antioxidants, SOD as canned food, fruit juice and other antioxidants, to prevent causing peroxidase the food spoilage and decay phenomenon, in addition to also serve as fruits, vegetables, good preservative;
(2) as a food fortifier, SOD resistant anti-aging characteristics can greatly improve the utilization of the food, especially as a pure anti-aging natural additives has been widely used at home and abroad. SOD as an additive, mainly used in mayonnalse , milk , soluble coffee , beer , chewin gum and so on.
3. SOD (superoxide dismutase) in daily cosmetics .
SOD added to cosmetics can play a role in four areas:
(1) there is a significant effect of sunscreen, light skin darkening is mainly due to oxygen free radical damage, SOD can effectively prevent skin by ionizing radiation (especially UV) damage, which play a sunscreen effect;
(2) SOD for the antioxidant enzyme, can effectively prevent skin aging, freckle, wrinkle;
(3) there are significant anti-inflammatory effects, prevention and treatment of skin diseases have a certain effect;
(4) SOD has a preventive role in scar formation.
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