Customization: | Available |
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CAS No.: | 519-02-8 |
Formula: | C15H24N2O |
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Matrine and oxymatrine are the two major alkaloid components found in sophora roots. They are obtained primarily from Sophora japonica (kushen), but also from Sophora subprostrata (shandougen), and from the above ground portion of Sophora alopecuroides. An intensive investigation into the pharmacology and clinical applications of these alkaloids has gone on for the past decade and remains one of the focal points of Chinese medical research. The mainclinical applications of matrine treatment of people with cancer, viral hepatitis, cardiac diseases, and skin diseases.
In China, matrine is often given by injection, but this method of administration is not acceptable in the West, so oral dosing is used here instead. When taken orally, much of the oxymatrine is converted to matrine; to get high blood levels of oxymatrine, it must be given by injection. However, it is unclear whether oxymatrine is clinically more effective than matrine. Chinese researchers have also used matrine in capsule form, with results that appear similar to the injection.
Items | Standards | Results |
Physical Analysis | ||
Description |
White Powder |
Complies |
Assay |
Matrine 4% (HPLC) |
4.32% |
Mesh Size | 100 % pass 80 mesh | Complies |
Ash | ≤ 5.0% | 3.82% |
Loss on Drying | ≤ 5.0% | 3.43% |
Chemical Analysis | ||
Heavy Metal | ≤ 10.0 mg/kg | Complies |
Pb | ≤ 2.0 mg/kg | Complies |
As | ≤ 1.0 mg/kg | Complies |
Hg | ≤ 0.1mg/kg | Complies |
Microbiological Analysis | ||
Residue of Pesticide |
Negative |
Negative |
Total Plate Count | ≤ 1000cfu/g | Complies |
Yeast&Mold | ≤ 100cfu/g | Complies |
E.coil | Negative | Negative |
Salmonella | Negative | Negative |
1. Sophora root extract matrine is also be widely used in pesticide;
2. Matrine has function of relieving internal heat;
3. Sophora root extract has effect on anti-bacteria, anti-inflammatory;
4. Matrine is used for suppressing sarcoma S180, anti-tumors;
5. Sophora root extract can cure tonsillitis, mastitis, smooth the asthma etc.when taken orally;
6. Sophora root extract can improve the leucocyte deficiency symptoms so as to enhance the body's immune function;
7. Sophora root extract is effective in dealing with trichomonad vaginitis, flagellate disease, amoeba dysentery and fungus dysentery, etc.
1. Applied in agriculture field, matrine can kill the pests.
Matrine is a natural plant-based pesticides, low toxicity for human and livestock, which is a broad spectrum insecticide with tag and stomach poison. It has a obvious control treatment effect on all kinds of crops NianChong, caterpillar, aphids, starscream.
2. Applied in pharmaceutical field, matrine is used for dispel heat, dry dampness, expel wind, and eliminate intestinal parasites, at the same time it also used to anti-bacteria, anti-inflammatory and anti-tumors.
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