1.Basic Information
| Product name |
5-Methoxytryptamine |
| CAS No |
608-07-1 |
| Appearance |
White crystal powder |
| Molecular formula |
C11H14N2O |
| Molecular weight |
190.24 |
| boiling point |
325.75°C |
| melting point |
121-123 °C |
| refractive index |
1.5700 |
| density |
1.0815 |
| Storage conditions |
2-8°C |
| Applications |
Melatonin Intermediate |
2.COA:
CERTIFICATE OF ANALYSIS
| Product name |
5-Methoxytryptamine |
Country of Origin |
China |
| Batch Size |
500KG |
Batch Number |
20220508 |
| Manufacture Date |
May 8, 2022 |
Expiry Date |
May 7, 2023 |
| ITEM |
STANDARD |
RESULT |
| Identification |
Positive reaction |
Conform |
| Loss on drying |
0.5% MAX |
0.04% |
| Sulphated Ash |
0.5% MAX |
0.06% |
| Color test |
0.5% Reference solution |
conform |
| Heavy metal |
20PPM MAX |
conform |
| Assay(HPLC) |
98.0% MIN |
99.12% |
Conclusion: Comply with the requirements of enterprise standard.
3.Source
5-Methoxytryptamine is a tryptamine derivative closely related to the neurotransmitters serotonin and melatonin. 5-Methoxytryptamine has been shown to occur naturally in the body at low levels. It is biosynthesized by deacetylation of melatonin in the pineal gland.
4.Function
5-Methoxytryptamine is a tryptamine derivative that is closely related to the neurotransmitters melatonin and serotonin. It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors, but has no affinity for the 5-HT3 receptor. It is a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors.
5.Application
The protective effect of 5-methoxytryptamine, a metabolite of melatonin, in human keratinocytes against ultraviolet B (UVB) has been investigated. 5-Methoxytryptamine as an agonist has been used in pharmacological studies of serotonin-1 receptors.
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