| CAS No.: | 545-47-1 |
|---|---|
| Formula: | C30H50O |
| EINECS: | 208-889-9 |
| Resource: | Natural |
| Transport Package: | 25 Kg/Carton Outside and Double Food Plastic Bags |
| Specification: | 8% |
| Samples: |
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| Customization: |
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Audited Supplier Lupinol is a pentacyclic anvil compound that can be extracted from a variety of fruits and vegetables such as strawberries and mangoes, as well as from plants such as Chinese herbs. It has pharmacological effects such as anti-inflammatory, antioxidant, and promotes wound healing, and has shown anti-cancer activity in tumors such as pancreatic cancer, breast cancer, prostate cancer, and melanoma, and is used clinically in the treatment of leukemia, liver cancer, colon cancer, pancreatic cancer, and other diseases.
Lupeol is a triterpene with a molecular weight of 426.72. Lupeol exists in the skin of lupine seeds, in the latex of fig trees and rubber plants, and is also widely found in fruits such as strawberries, mangoes, grapes, and olives.
Lupeol is a pentacyclic and three-anvil compound that can be extracted from various fruits and vegetables such as strawberries, mangoes, and Chinese herbal medicines. 
| Product Name | Lupinol |
| Specification | 8% |
| Appearance | White to off-white powder |
| CAS No. | 545-47-1 |
| Molecular formula | C30H50O |
| Molecular weight | 426.73 |
| EINECS No. | 208-889-9 |
| Melting point | 215°C |
| Boiling point | 482.1 (rough estimate) |
1. Anti-tumor effects
(1)Inhibitory effect on melanoma
Lupinol has an inhibitory effect on the growth and induction of differentiation of mouse melanoma.
(2) Inhibitory effect on skin cancer in mice
Lupinol has an inhibitory effect on the development of skin cancer and the expression of its tumor markers.
(3) Inhibitory effect on breast cancer
Lupinol has an inhibitory effect on the growth of breast cancer cells.
(4) Inhibitory and apoptosis-inducing effects on prostate cancer cells
Among endocrine-related tumors, in addition to breast cancer cells, lupinol also has an inhibitory effect on prostate cancer.
(5) Inhibitory and apoptosis-inducing effects on pancreatic cancer
Lupinol has a growth inhibitory effect on pancreatic cancer, and inhibition of the Ras pathway induces apoptosis in pancreatic cancer cells.
(6) Inhibitory effect on hepatocellular carcinoma cells
Lupinol inhibits the self-renewal ability of tumorinitiating cells (TIC) in vitro and in vivo.
(7) Inhibitory effect on leukemia cells
Lupinol has a growth inhibitory and apoptosis-inducing effect on leukemia cells. The inhibitory effect of lupinol on leukemia cells is related to the carbonylation of lupin ring.
(8) Inhibitory effects on other tumors
Lupinol has an inhibitory effect on head and neck tumors. Lupinol has an inhibitory effect on human ovarian cancer cells.
3.Antioxidant effect
| Product Name | Lupeol | ||
| Batch No. | SOST20220827 | Quantity | 50Kg |
| Manufacturing Date | 20220827 | Test Date | 20220830 |
| Expiry Date | 20240826 | Package | 25 Kg/Drum |
| Storage condition | Store with seal at room temperature | ||
| Items | Standards | Results |
| Purity(HPLC) | Lupeol≥98% | 98.6% |
| Appearance | White powder | Conforms |
| Physical characteristics | ||
| Particle-size | NLT100% 80 | Conforms |
| Loss on drying | ≤2.0% | 1.54% |
| Heavy metal | ||
| Total metals | ≤10.0ppm | Conforms |
| Lead | ≤2.0ppm | Conforms |
| Mercury | ≤1.0ppm | Conforms |
| Cadmium | ≤0.5ppm | Conforms |
| Microorganism | ||
| Total number of bacteria | ≤1000cfu/g | Conforms |
| Yeast | ≤100cfu/g | Conforms |
| Escherichia coli | Not included | |
| Salmonella | Not included | Not detected |
| Staphylococcus | Not included | Not detected |
| Conclusions | Qualified | |
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