| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S.and as Transamin,Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid.
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Items |
Standards |
Results |
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Physical Analysis |
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Description |
White Powder | Complies |
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Assay |
99% | 99.12% |
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Mesh Size |
100 % pass 80 mesh | Complies |
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Ash |
≤ 5.0% | 2.85% |
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Loss on Drying |
≤ 5.0% | 2.65% |
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Chemical Analysis |
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Heavy Metal |
≤ 10.0 mg/kg |
Complies |
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Pb |
≤ 2.0 mg/kg |
Complies |
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As |
≤ 1.0 mg/kg | Complies |
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Hg |
≤ 0.1mg/kg | Complies |
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Microbiological Analysis |
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Residue of Pesticide |
Negative | Negative |
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Total Plate Count |
≤ 1000cfu/g | Complies |
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Yeast&Mold |
≤ 100cfu/g | Complies |
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E.coil |
Negative |
Negative |
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Salmonella |
Negative |
Negative |
1. Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver,vascular and large orthopedic procedures.
2. Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury.
1. Menstrual bleeding
Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysinebinding sites on plasminogen molecules.Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.
Tranexamic acid is used as firstline nonhormonal treatment of dysfunctional uterine bleeding,and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.
2. Orthopedic Surgery
Tranexamic acid is used in orthopedic surgery to reduce bloodloss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.
3. Trauma
Tranexamic acid should be considered for use in bleeding trauma patients.
4. Dentistry
Tranexamic acid is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
| Recommended transportation selections | ||
| By Express | By Air Transportation | By Sea Transportation |
| Suitable for sample order or <50kg Fast: 3-10 days High shipping cost Door to door service |
Suitable for >50kg Fast: 3-7 days Lower than express cost Airport to airport service Professional broker needed |
Suitable for > 300kg Slow: 7-45 days Lowest cost Port to port service Professional broker needed |
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