| Customization: | Available |
|---|---|
| Shelf Life: | 24 Months |
| CAS NO.: | 49557-75-7 |
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Blue Copper Peptide was isolated from human plasma by Pickart et al. in 1973, and is composed of a complex of tripeptide-1 and Cu2+(copper ion). Its chemical structural formula contains the His Lys Arg sequence, and copper ions form a six coordinate complex with the peptide chain through coordination bonds
Endow it with unique biological activity. As a carrier peptide, blue copper peptide plays a dual role as a growth factor and extracellular matrix regulator in biology.
1. Promote the regeneration of collagen and elastin
Blue copper peptide activates signaling pathways such as MAPK/ERK, PI3K/AKT, etc., stimulating fibroblast secretion of collagen and elastin, promoting inhibition of skin matrix metalloproteinases (MMPs), reducing collagen degradation, and achieving a reversal from "degradation of old collagen" to "synthesis of new collagen".
2. Wound healing and cell repair
Blue copper peptide has significant healing promoting properties, which can accelerate the proliferation of keratinocytes, inhibit the synthesis of inflammatory factors IL-6 and TNF - α, and thus reduce inflammatory reactions. In vitro experiments have shown that it can induce the expression of DNA damage repair related genes and exhibit a protective effect in a UV damage model.
3. Gene expression regulation
Blue copper peptide regulates cellular metabolism at the molecular level by affecting the transcription of approximately 4000 genes. Its mechanism of action partially involves the inhibition of transcription factors such as NF - κ B and AP-1, and long-term use may reshape the skin microbiota and immune response.
For the repair needs of sensitive muscles, blue copper peptide is often compounded with the following ingredients:
1. Ectoine
2. Centella Asiatica Extract
The triterpenoids in centella asiatica, such as centella asiatica glycoside, promote skin stem cell proliferation by activating the ERK1/2 pathway, while inhibiting MMP activity and reducing scar formation. Its firming effect on the skin is due to the upregulation of collagen type I and III mRNA.
3. Panthenol
As a precursor of coenzyme A, panthenol participates in NADPH regeneration Its unique cell differentiation function can accelerate the repair of keratinocytes after sunburn, while strengthening the skin barrier function and reducing transcutaneous dehydration rate (TEWL).
4. Glycerol glucoside
Extracting natural glycosides from resurrection grass as multifunctional cell activators, it achieves a synergistic effect of "water capture water storage water lock" by promoting the expression of aquaporins such as AQP3. Its water retention ability is particularly significant in dry environments, which can increase the moisture content of the stratum corneum by 30% -50%.
| Recommended transportation selections | ||
| By Express | By Air Transportation | By Sea Transportation |
| Suitable for sample order or <50kg Fast: 3-10 days High shipping cost Door to door service |
Suitable for >50kg Fast: 3-7 days Lower than express cost Airport to airport service Professional broker needed |
Suitable for > 300kg Slow: 7-45 days Lowest cost Port to port service Professional broker needed |
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