1.Basic Information:
| Product Name |
Indole-3-Carbinol
|
| Character |
White crystals powder |
| Dry weight |
≤0.5% |
| CAS No. |
700-06-1 |
| Molecular |
C9H9NO |
| Molecular weight |
147.18 |
| Boiling point |
360.6ºC at 760 mmHg |
| Melting point |
96-99ºC |
| Flash point |
171.9ºC |
| Density |
1.272 g/cm3 |
| Dry weight |
≤0.5% |
| Storage condition |
2-8°C |
| Application |
Medicine intermediate, with totane scholes, antiviral drugs. |
2.COA:
CERTIFICATE OF ANALYSIS
| Product name |
DI-INDOLYMETHANE |
Country of Origin |
China |
| Batch Size |
500KG |
Batch Number |
20210508 |
| Manufacture Date |
May 8, 2022 |
Expiry Date |
May 7, 2023 |
| Items |
Specification |
Results |
| Description |
Off-white to white crystalline powder |
White |
| Assay(By HPLC) |
≥98% |
99.30% |
| Sulfated Ash |
≤0.1% |
0.06% |
| Melting Range |
165.0ºC~169.0ºC |
166ºC~168ºC |
| Loss on Drying |
≤0.50% |
0.3% |
| Lead |
NMT 2 ppm |
Conforms |
| Benzene |
NMT 2 ppm |
Conforms |
| Arsenic |
NMT 2 ppm |
Conforms |
| Solvent of Used |
Ethanol |
Conforms |
| Microbiolgical Control |
| Total Plate Count |
≤500cfu/g |
Conforms |
| Moulds |
≤100cfu/g |
Conforms |
| Salmonella |
Negative |
Negative |
| E.Coli |
Negative |
Negative |
| Pseudomonas |
Negative |
Negative |
| Staphylococcus |
Negative |
Negative |
| Melamine |
Negative |
Negative |
| Storage |
Cool & dry place, Keep away from strong light and heat. |
| Shelf |
2 years when properly stored |
Conclusion: The product conforms with the above specification.
3.Source:
Indole-3-Carbinol is broken down by moss glucosulidoside.
Moss glucosulidin is a species of glucoside, and sulfurin glycoside is widely existed in the plants of the family.
Foods such as west blue flowers, west blue flower seedlings, cabbage, cauliflower, and housing cabbage family can produce Indole-3-Carbinol under the action of black mustard.
4.Efficacy and Role Mechanism:
*Anti -cancer
Studies have found that 3 -3-methanol can inhibit tumors in various ways, such as inducing apoptosis of cancer cells, cell cycles that hinder cancer cells, and downgosted estrogen.
*Regulate estrogen:
Among women, the level of estrogen is too high, and other sex hormones are relatively insufficient, which will cause many problems, including menstrual disorders, fatigue, PMS, and increase the risk of hormones such as breast cancer. The Indole-3-Carbinol can inhibit the synthesis of estrogen, block the pathway related to estrogen, and inhibit cell proliferation caused by estrogen.
Among women, the level of estrogen is too high, and other sex hormones are relatively insufficient, which will cause many problems, including menstrual disorders, fatigue, PMS, and increase the risk of hormones such as breast cancer. The can inhibit the synthesis of estrogen, block the pathway related to estrogen, and inhibit cell proliferation caused by estrogen.
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