Microbial Fermentation Anti-Aging Ergothioneine Powder (EGT)

• Powder: Yes
• Customized: Customized
• Certification: ISO 9001
• Suitable for: Adult
• State: Solid
• Purity: >97%
• Transport Package: 1.1 Kilogram Per Aluminum Foil Bag with One Plast
• Specification: 98%
• Trademark: SOST
• Origin: China
• Production Capacity: 1 Ton

Product Description

What Is Ergothioneine?
Ergothioneine (mercaptohistidine trimethyl inner salt, ergothioneine, EGT) is a compound discovered in 1909, originally found in a fungus Claviceps purpurea, pure white crystals, water-soluble, (at room temperature Soluble 0.9mol/L), will not self-oxidize under physiological pH value and strong alkaline solution. It exists in two isomers, thiol and thione.
Ergothioneine is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. It can remove high concentrations of free radicals produced by the human body, reduce pigmentation, increase skin elasticity, and slow down aging.
Ergothioneine is a rare natural amino acid. The human body cannot synthesize ergothioneine by itself and can only be taken from the diet.
EGT is an important physiologically active substance in the body, which plays a variety of functions such as anti-oxidation, scavenging free radicals, preventing ultraviolet radiation damage, regulating intracellular redox reactions, participating in intracellular energy regulation and cell physiological protective agent.
Recent scientific research has proved that EGT can protect the nuclear DNA by entering human cells and even the nucleus, so some people call it a cell guardian, and some scientists propose that EGT can be used as a new vitamin.
EGT is a natural substance that epidermal cells like very much. In addition, L-EGT can protect vitamin C in the human body from being rapidly oxidized, and can reduce the activity of vitamin C.

Basic Information

CAS No.	497-30-3
Molecular formula	C9H15N3O2S
Molecular weight	229.3
Melting point	275-277ºC
EINECS No.	207-843-5
Density	1.2541
Storage condition	20ºC
Refractive index	1.6740
Appearance	White Powder
Water Solubility	Soluble in water
Test Method	HPLC
Mesh Size	80
Shelf Life	24 Months

Function
1. Antioxidant effect
Ergothioneine is a natural amino acid that is derived from plants and can be accumulated in animals. Studies have shown that it has the effect of antioxidants. It can effectively remove -OH, chelate ferrous ions and copper ions. It generates -OH under the action of iron ions or copper ions, and can also inhibit the oxidation of copper ion-dependent oxyhemoglobin. Ergothioneine also potently scavenges hypochlorous acid, thereby preventing the inactivation of a 1-antiprotease. However, it cannot inhibit the peroxidation of lipid particles in the presence of iron ions. Research by AKanmu D et al. showed that a certain concentration of ergothioneine can act as an antioxidant in the body.
2. Protective effect on cells
Ergothioneine is a powerful hypochlorous acid scavenger (HOCl), and while many compounds react with hypochlorous acid, few react as rapidly as ergothioneine. a 1-Antiprotease inhibitors (APIs), such as elastase, are particularly sensitive to hypochlorous acid, while ergothioneine at physiological concentrations is very effective in protecting APIs against inactivation by hypochlorous acid, due to the Neutrophils are the main source of hypochlorous acid in the body, and one of the effects of ergothioneine is to protect red blood cells from harm from neutrophils from normal function or from sites of diseased inflammation.
3. Anti-inflammatory effect
Peroxynitrite is endogenously formed by the limited diffusion reaction of NO and superoxide, and is a strong oxidant involved in the pathophysiology of inflammation, such as ischemia-reperfusion injury, atherosclerosis, acute pneumonia, and sepsis. Ergothioneine can inhibit peroxynitrite-mediated amino acid oxidation, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.

Application
Ergothioneine has strong antioxidant activity: scavenging reactive oxygen species, chelating divalent metal ions, activating antioxidant enzymes, inhibiting superoxide dismutase, inhibiting the oxidation of various heme proteins, etc. Due to these properties of ergothioneine, it has a wide range of uses and market prospects in the fields of medicine, food and beverage, functional food, animal feed, cosmetics and biotechnology.